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Spherocytosis

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Hereditary
Condition
Diagnosis
Treatment
Related
Conditions
1 Hereditary Spherocytosis, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee
Auteur : Kenneth Kee
Genre : Medical
This book describes Hereditary Spherocytosis, Diagnosis and Treatment and Related Diseases
Hereditary spherocytosis is a rare medical disorder of the surface layer of red blood cells.
It results in red blood cells that appear like spheres, and causes premature breakdown of red blood cells (hemolytic anemia).
It may manifest as a collection of inherited disorders which present as spherical-shaped erythrocytes (spherocytes) on the peripheral blood smear
Causes
This disorder is produced by a defective gene.
The defect leads to an abnormal red blood cell membrane.
The involved cells have a reduced surface area for their volume than normal red blood cells, and can rupture easily.
The anemia can range from mild to severe.
The medical severity differs (depending on the mutation), from asymptomatic to a life-threatening hemolytic anemia
All mutat
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